SPL Set ID: 905503ef-4277-44ca-aa4a-5a969a041e16

Ciprofloxacin for Oral Suspension, USP is a synthetic antimicrobial agent for oral administration. Ciprofloxacin hydrochloride, USP, a fluoroquinolone, is the monohydrochloride monohydrate salt of 1-cyclopropyl-6-fluoro-1, 4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid. It is a faintly yellowish to light yellow crystalline substance with a molecular weight of 385.8. Its empirical formula is C 17 H 18 FN 3 O 3 •HCl•H 2 O and its chemical structure is as follows: Ciprofloxacin is 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid. Its empirical formula is C 17 H 18 FN 3 O 3 and its molecular weight is 331.4. It is a faintly yellowish to light yellow crystalline substance and its chemical structure is as follows: Ciprofloxacin for Oral Suspension, USP is available in 5% (5 g ciprofloxacin in 100 mL) and 10% (10 g ciprofloxacin in 100 mL) strengths. Ciprofloxacin for Oral Suspension, USP is White to cream colored granular blend on reconstitution gives white yellow colored suspension with strawberry flavor. It is composed of ciprofloxacin granular blend and diluent which are mixed prior to dispensing [see Dosage and Administration ( 2.5 )] . The components of the suspension have the following compositions: Granular blend - amino methacrylate copolymer, croscarmellose sodium, hydrophobic fumed silica, hypromellose, sucrose and talc. Diluent - flavour strawberry, hydrophobic fumed silica, lecithin, medium chain triglycerides, polysorbate 20, sucralose, and sucrose. Five (5) mL of 5% suspension contains approximately 1.35 g of sucrose and 5 mL of 10% suspension contains approximately 0.693 g of sucrose. chem struc 1 chem struc 2