SPL Set ID: 861247cc-3edf-4497-b230-2147489548b3

1 drug(s) with this SPL Set ID

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Nicardipine Hydrochloride NICARDIPINE HYDROCHLORIDE
ZYDUS PHARMACEUTICALS USA INC. FDA Rx Only

Nicardipine hydrochloride capsules for oral administration each contain 20 mg or 30 mg of nicardipine hydrochloride, USP. Nicardipine hydrochloride capsules are a calcium ion influx inhibitor (slow channel blocker or calcium channel blocker). Nicardipine hydrochloride, USP is a dihydropyridine structure with the IUPAC (International Union of Pure and Applied Chemistry) chemical name 2-(benzyl-methyl amino)ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate monohydrochloride, and it has the following structure: Nicardipine Hydrochloride, USP Molecular Formula C 26 H 29 N 3 O 6 . HCl Nicardipine hydrochloride, USP is a pale greenish-yellow, odorless, crystalline powder that melts at about 167°C to 171°C. It is freely soluble in methanol and acetic acid, sparingly soluble in ethanol, slightly soluble in water. It has a molecular weight of 515.99. Nicardipine hydrochloride capsules are available in hard gelatin capsules containing 20-mg or 30-mg nicardipine hydrochloride, USP with magnesium stearate and pregelatinized starch as the inactive ingredients. The 20-mg strength is provided in opaque light blue cap and opaque white body, while the 30-mg capsules are provided in opaque blue cap and opaque light blue body. The capsule shells contains gelatin, titanium dioxide, and FD&C Blue No. 1. The black imprinting ink contains black iron oxide, potassium hydroxide and shellac. Image

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