SPL Set ID: 85bfe02b-bfcb-44ee-81a0-11765c3054a9

Celecoxib capsules is a nonsteroidal anti-inflammatory drug, available as capsules containing 50 mg, 100 mg, 200 mg and 400 mg celecoxib for oral administration. The chemical name is 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl] benzenesulfonamide and is a diaryl-substituted pyrazole. The molecular weight is 381.38. Its molecular formula is C 17 H 14 F 3 N 3 O 2 S, and it has the following chemical structure: Celecoxib is a white to off-white powder with a pKa of 11.1 (sulfonamide moiety). Celecoxib is hydrophobic (log P is 3.5) and is practically insoluble in aqueous media at physiological pH range. The inactive ingredients in celecoxib include: black iron oxide, croscarmellose sodium, FD&C blue #1, FD&C red #40, gelatin, lactose monohydrate, magnesium stearate, potassium hydroxide, povidone, propylene glycol, shellac, sodium lauryl sulphate, titanium dioxide, red iron oxide and yellow iron oxide. image-01