SPL Set ID: 81686d37-a13f-46e2-b439-a84eb1433634

Docetaxel is an antineoplastic agent belonging to the taxoid family. It is prepared by semisynthesis beginning with a precursor extracted from the renewable needle biomass of yew plants. The chemical name for docetaxel is (2R,3S)-N-carboxy-3-phenylisoserine,N- tert -butyl ester, 13-ester with 5β-20-epoxy-1,2α,4,7β,10β,13α-hexahydroxytax-11-en-9-one 4-acetate 2-benzoate. Docetaxel has the following structural formula: Docetaxel is a white to almost-white powder with an empirical formula of C43H53NO14, and a molecular weight of 807.88. It is highly lipophilic and practically insoluble in water. One-vial Docetaxel Injection Docetaxel Injection is a sterile, non-pyrogenic, and colourless to brownish yellow clear solution at 20 mg/mL concentration. Each mL contains 20 mg docetaxel (anhydrous) in 0.54 grams polysorbate 80 and 0.395 grams dehydrated alcohol (50% v/v) solution, with 0.7 mg anhydrous citric acid for pH adjustment. Docetaxel Injection is available in single-dose vials containing 20 mg (1 mL), 80 mg (4 mL) or 160 mg (8mL). Docetaxel Injection requires NO prior dilution with a diluent and is ready to add to the infusion solution for injection. structural formula