SPL Set ID: 7f7ed64d-8480-4143-a207-29c24a0b9363

LOKELMA is a powder for oral suspension. The active ingredient in LOKELMA is sodium zirconium cyclosilicate, a potassium binder. Sodium zirconium cyclosilicate is a non-absorbed zirconium silicate that preferentially exchanges potassium for hydrogen and sodium. LOKELMA is an odorless, insoluble white to grey powder for oral suspension. It has a mean particle size of 20 µm and includes no more than 3% of particles with a diameter below 3 µm. Each 5 g of sodium zirconium cyclosilicate contains 400 mg of sodium. The chemical formula of sodium zirconium cyclosilicate is Na ~1.5 H ~0.5 ZrSi 3 O 9 •2–3H 2 O. Figure 1: Crystal Structure of Sodium Zirconium Cyclosilicate Figure 1