SPL Set ID: 7c0d3bcb-157d-0414-64ee-055bc614d190
1 drug(s) with this SPL Set ID
Donepezil hydrochloride monohydrate USP is a reversible inhibitor of the enzyme acetylcholinesterase, known chemically as (±)-2, 3-dihydro-5, 6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one hydrochloride monohydrate. Donepezil hydrochloride monohydrate USP is commonly referred to in the pharmacological literature as E2020. It has an molecular formula of C 24 H 29 NO 3 HCl.H 2 O and a molecular weight of 433.95. Donepezil hydrochloride monohydrate USP is a off-white to white crystalline powder and is soluble in chloroform, water and in glacial aceticacid, slightly soluble in alcohol and acetonitrile, practically insoluble in ethyl acetate and n-Hexane. Donepezil hydrochloride tablets, USP are available for oral administration in film-coated tablets containing 23 mg of donepezil hydrochloride monohydrate USP. Inactive ingredients are hydroxypropyl cellulose, hypromellose, lactose monohydrate, magnesium stearate and methacrylic acid copolymer. The film coating includes iron oxide red, iron oxide yellow and Opadry OY-58900 White contains hypromellose, polyethylene glycol and titanium dioxide.