SPL Set ID: 7ab9d0ef-e30c-46e9-9911-435a7b65c47b
1 drug(s) with this SPL Set ID
Donepezil is a reversible inhibitor of the enzyme acetylcholinesterase, known chemically as (±)-2, 3-dihydro-5, 6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1 H -inden-1-one . Donepezil is commonly referred to in the pharmacological literature as E2020. It has a molecular formula of C 24 H 29 NO 3 HCl and a molecular weight of 415.96. Donepezil USP is a white to off-white powder and is freely soluble in chloroform, soluble in water and in glacial acetic acid, slightly soluble in ethanol and in acetonitrile and practically insoluble in ethyl acetate and in n-hexane. Donepezil hydrochloride USP is available for oral administration in tablets containing 5 mg or 10 mg of donepezil hydrochloride USP. Inactive ingredients are croscarmellose sodium, lactose, magnesium stearate, and microcrystalline cellulose.