SPL Set ID: 78bdb7ca-acb0-491c-bed9-4ebbf2a07918
1 drug(s) with this SPL Set ID
Betamethasone Dipropionate Cream (augmented), 0.05% contains betamethasone dipropionate, USP, a synthetic adrenocorticosteroid, for topical use in an emollient cream base. Betamethasone, an analog of prednisolone, has a high degree of corticosteroid activity and a slight degree of mineralocorticoid activity. Betamethasone dipropionate is the 17,21-dipropionate ester of betamethasone. Chemically, betamethasone dipropionate, USP is 9-fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate, with the molecular formula C 28 H 37 FO 7 , a molecular weight of 504.6 g/mol, and the following structural formula: Betamethasone dipropionate, USP is a white or almost white crystalline powder, insoluble in water, freely soluble in acetone and in methylene chloride, sparingly soluble in alcohol. Each gram of Betamethasone Dipropionate Cream (augmented), 0.05% contains: 0.643 mg betamethasone dipropionate, USP (equivalent to 0.5 mg betamethasone) in a white to off-white, uniform and smooth cream base of carbomer homopolymer, ceteareth-30, chlorocresol, cyclomethicone, glyceryl oleate/propylene glycol, purified water, propylene glycol, sodium hydroxide, sorbitol solution, white petrolatum and white wax. structure