SPL Set ID: 7066d371-dc6a-0d6f-7bed-e5dd4ee912da

1 drug(s) with this SPL Set ID

Open DailyMed details

Duopa CARBIDOPA AND LEVODOPA
ABBVIE INC. FDA Rx Only

DUOPA is a combination of carbidopa, an inhibitor of aromatic amino acid decarboxylation, and levodopa, an aromatic amino acid. Carbidopa is a white, crystalline compound, slightly soluble in water, with a molecular weight of 244.2. It is designated chemically as (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazino-2-methylpropanoic acid monohydrate. Its empirical formula is C 10 H 14 N 2 O 4 •H 2 O, and its structural formula is: The content of carbidopa in DUOPA is expressed in terms of anhydrous carbidopa which has a molecular weight of 226.3. The 4.63 mg/mL of anhydrous carbidopa is equivalent to 5.0 mg/mL of carbidopa. Levodopa is a white, crystalline compound, slightly soluble in water, with a molecular weight of 197.2. It is designated chemically as (2S)-2-Amino-3-(3,4-dihydroxyphenyl) propanoic acid. Its empirical formula is C 9 H 11 NO 4 , and its structural formula is: The inactive ingredients in DUOPA are carmellose sodium and purified water. carbidopa chem structure levodopa chem structure

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