SPL Set ID: 6da7501b-b881-4bc7-891a-74214a00a3ac
1 drug(s) with this SPL Set ID
Methadone hydrochloride tablets contain methadone, an opioid agonist, available as 5 and 10 mg tablets for oral administration. Methadone hydrochloride is chemically described as 6-(dimethylamino)-4,4-diphenyl-3-hepatanone hydrochloride. Methadone hydrochloride USP is a white, crystalline material that is water-soluble. Its molecular formula is C 21 H 27 NO• HCl and it has a molecular weight of 345.91. Methadone hydrochloride has a melting point of 235°C, and a pKa of 8.25 in water at 20°C. Its octanol/water partition coefficient at pH 7.4 is 117. A solution (1:100) in water has a pH between 4.5 and 6.5. It has the following structural formula: Each methadone hydrochloride tablet contains 5 or 10 mg of methadone hydrochloride USP and the following inactive ingredients: magnesium stearate, microcrystalline cellulose, and pregelatinized starch. structural formula