SPL Set ID: 674e0e6d-46ed-4868-9196-04019d667716
1 drug(s) with this SPL Set ID
NIPENT ™ (pentostatin for injection) is supplied as a sterile, apyrogenic, lyophilized powder in single-dose vials for intravenous administration. Each vial contains 10 mg of pentostatin and 50 mg of Mannitol, USP. The pH of the final product is maintained between 7.0 and 8.5 by addition of sodium hydroxide or hydrochloric acid. Pentostatin, also known as 2'-deoxycoformycin (DCF), is a potent inhibitor of the enzyme adenosine deaminase and is isolated from fermentation cultures of Streptomyces antibioticus . Pentostatin is known chemically as (R)-3-(2-deoxy-ß-D-erythropentofuranosyl)3,6,7,8 tetrahydroimidazo[4,5d][1,3]diazepin-8-ol with a molecular formula of C 11 H 16 N 4 O 4 and a molecular weight of 268.27. The molecular structure of pentostatin is: Pentostatin is a white to off-white solid, freely soluble in distilled water. structural formula pentostatin