SPL Set ID: 6514e849-b6de-4c32-bc36-0e3a5b431cee
1 drug(s) with this SPL Set ID
Eplerenone tablets contains eplerenone, a blocker of aldosterone binding at the mineralocorticoid receptor. Eplerenone is chemically described as Pregn-4-ene-7,21-dicarboxylic acid, 9,11-epoxy-17-hydroxy-3‑oxo-, γ-lactone, methyl ester, (7α,11α,17α)-. Its empirical formula is C 24 H 30 O 6 and it has a molecular weight of 414.50. The structural formula of eplerenone is represented below: Eplerenone is white or almost white powder. It is freely soluble in dichloromethane, very slightly soluble in water. The octanol/water partition coefficient of eplerenone is approximately 7.1 at pH 7.0. Eplerenone tablets for oral administration contain 25 mg or 50 mg of eplerenone and the following inactive ingredients: lactose monohydrate, microcrystalline cellulose, croscarmellose sodium, hypromellose, sodium lauryl sulfate, talc, magnesium stearate, titanium dioxide, polyethylene glycol 400, polysorbate 80. In addition, the 50 mg tablets contain iron oxide yellow and iron oxide red. eplerenone-formula-1.jpg