SPL Set ID: 645d34d9-275d-428e-863d-ae15ad009c44

Tobramycin sulfate, a water-soluble antibiotic of the aminoglycoside group, is derived from the actinomycete Streptomyces tenebrarius . Tobramycin Injection, USP is a clear and colorless sterile aqueous solution for parenteral administration. Each mL contains tobramycin sulfate equivalent to 10 mg or 40 mg tobramycin for Tobramycin Injection USP, 10 mg/mL (Pediatric) or 40 mg/mL; sodium metabisulfite added as an antioxidant, 3.2 mg; and edetate disodium added as a stabilizer, 0.1 mg. Contains sulfuric acid and may contain sodium hydroxide for pH adjustment. pH 4.0 (3.0 to 6.5). Tobramycin sulfate is O -3-amino-3-deoxy- α -D-glucopyranosyl-(1→4)- O -[2,6-diamino-2,3,6-trideoxy- α -D- ribo -hexopyranosyl-(1→6)]-2-deoxy-L-streptamine (2:5) (salt) and has the chemical formula (C 18 H 37 N 5 O 9 ) 2 • 5H 2 SO 4 . The molecular weight is 1,425.39. The structural formula for tobramycin is as follows: tobramycin-spl-structure