SPL Set ID: 5e09acc0-fd26-4722-b8b3-46e560390d47
1 drug(s) with this SPL Set ID
Mifepristone is a cortisol receptor blocker for oral administration. The chemical name of mifepristone is 11β-(4-dimethylaminophenyl)-17β-hydroxy-17α-(1-propynyl)-estra-4, 9-dien-3-one. The molecular formula is C 29 H 35 NO 2 ; the molecular weight is 429.60, and the structural formula is: Mifepristone demonstrates a pH-related solubility profile. The greatest solubility is achieved in acidic media (~ 25 mg/mL at pH 1.5) and solubility declines rapidly as the pH is increased. At pH values above 2.5 the solubility of mifepristone is less than 1 mg/mL. Each mifepristone tablet for oral use contains 300 mg of mifepristone. The inactive ingredients of mifepristone tablets are FD&C Blue #1 Brilliant Blue FCF Aluminum Lake, FD&C Yellow #5 (tartrazine) Aluminum Lake, FD&C Yellow #6 Sunset Yellow FCF Aluminum Lake, hydroxypropyl cellulose, hypromellose, magnesium stearate, polysorbate 80, microcrystalline cellulose, sodium lauryl sulfate, sodium starch glycolate type A, titanium dioxide, and triacetin. 1