SPL Set ID: 5de44ee7-6525-4857-9a67-8882e96dbeb5
1 drug(s) with this SPL Set ID
Naloxone hydrochloride injection USP, an opioid antagonist, is a synthetic congener of oxymorphone. In structure it differs from oxymorphone in that the methyl group on the nitrogen atom is replaced by an allyl group. Naloxone hydrochloride, USP occurs as a white to slightly off-white powder, and is soluble in water, in dilute acids, and in strong alkali; slightly soluble in alcohol; practically insoluble in ether and in chloroform. Naloxone hydrochloride injection, USP is available as a sterile, clear colorless solution for intravenous, intramuscular, or subcutaneous administration in the concentration 1 mg of naloxone hydrochloride per mL. pH is adjusted to 3.0 to 5.0 with hydrochloric acid. The 1 mg/mL single dose prefilled syringe is available in an unpreserved, paraben-free formulation containing 8.35 mg/mL of sodium chloride. structure