SPL Set ID: 5cec3b97-5183-4a9d-accd-21e76c99d3dd
1 drug(s) with this SPL Set ID
DIPRIVAN ® (propofol) injectable emulsion, USP is a sterile, nonpyrogenic emulsion containing 10 mg/mL of propofol suitable for intravenous administration. Propofol is chemically described as 2,6‑diisopropylphenol. The structural formula is: Propofol is slightly soluble in water and, thus, is formulated in a white, oil-in-water emulsion. The pKa is 11. The octanol/water partition coefficient for propofol is 6761:1 at a pH of 6 to 8.5. In addition to the active component, propofol, the formulation also contains soybean oil (100 mg/mL), glycerol (22.5 mg/mL), egg lecithin (12 mg/mL); and disodium edetate anhydrous (0.05 mg/mL); with sodium hydroxide to adjust pH. DIPRIVAN is isotonic and has a pH of 7 to 8.5. dipr struct