SPL Set ID: 5baef1bf-8bf0-429c-a4ce-1c93171f3f15
1 drug(s) with this SPL Set ID
Methadone hydrochloride is chemically described as 6-(dimethylamino)-4,4-diphenyl-3-hepatanone hydrochloride. Methadone hydrochloride USP is a white powder that is water-soluble. Its molecular formula is C 21 H 27 NO ∙ HCl and it has a molecular weight of 345.91. Methadone hydrochloride has a melting point of 235°C, and a pKa of 8.25 in water at 20°C. Its octanol/water partition coefficient at pH 7.4 is 117. A solution (1:100) in water has a pH between 4.5 and 6.5. It has the following structural formula: Each 5 mL of methadone hydrochloride oral solution contains 5 mg or 10 mg of methadone hydrochloride USP and the following inactive ingredients: artificial raspberry flavor, citric acid anhydrous, FD&C Red #40, FD&C Yellow #6, glycerin, propylene glycol, purified water, saccharin sodium, sodium benzoate, sorbitol solution, and sucrose. May contain sodium citrate to adjust pH. Chemical Structure