SPL Set ID: 595821d7-1fbf-49a5-9c62-d78f27af39b4
1 drug(s) with this SPL Set ID
Ranolazine extended-release tablets are available as a film-coated, non-scored, extended-release tablet for oral administration. Ranolazine is a racemic mixture, chemically described as 1-piperazineacetamide, N -(2, 6-dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-, (±)-. It has molecular formula of C 24 H 33 N 3 O 4 , a molecular weight of 427.54 g/mole, and the following structural formula: Ranolazine is a white to off-white solid. Ranolazine is soluble in dichloromethane and methanol; sparingly soluble in tetrahydrofuran, ethanol, acetonitrile, and acetone; slightly soluble in ethyl acetate, isopropanol, toluene, and ethyl ether; and very slightly soluble in water. Ranolazine extended-release tablets contain 500 mg or 1000 mg of ranolazine and the following inactive ingredients: colloidal silicon dioxide, lactose monohydrate, magnesium stearate, methacrylic acid co-polymer type C, microcrystalline cellulose, sodium alginate, sodium hydroxide. Additional inactive ingredients used in film coating for the 500 mg tablet include FD&C yellow #6, hypromellose, polyethylene glycol, talc and titanium dioxide; additional inactive ingredients used in film coating for the 1000 mg tablet include hypromellose, iron oxide yellow, polyethylene glycol 4000 and titanium dioxide. Ranolazine