SPL Set ID: 58af9a98-b1a1-4f30-b535-6647f1effed4
1 drug(s) with this SPL Set ID
Silodosin is a selective antagonist of alpha-1 adrenoreceptors. The chemical name of silodosin is (R)-1-(3-hydroxypropyl)-5-(2-(2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethylamino)propyl) indoline-7-carboxamide and the molecular formula is C 25 H 32 F 3 N 3 O 4 with a molecular weight of 495.53. The structural formula of silodosin is: Silodosin is a white to pale yellowish colour powder that melts at approximately 105 to 109°C. It is very soluble in acetic acid, freely soluble in alcohol, and very slightly soluble in water. Each silodosin 8 mg capsule for oral administration contains 8 mg silodosin, and the following inactive ingredients: mannitol, magnesium stearate, pregelatinized starch (maize), and sodium lauryl sulfate. The size #1 hard gelatin capsules contain gelatin, titanium dioxide and sodium lauryl sulfate. The capsules are printed with edible ink containing shellac, propylene glycol, FD&C Blue No. 1 Aluminum Lake and yellow iron oxide. Each silodosin 4 mg capsule for oral administration contains 4 mg silodosin, and the following inactive ingredients: mannitol, magnesium stearate, pregelatinized starch (maize), and sodium lauryl sulfate. The size #3 hard gelatin capsules contain gelatin, titanium dioxide and sodium lauryl sulfate. The capsules are printed with edible ink containing shellac, propylene glycol and yellow iron oxide. 333