SPL Set ID: 559cca31-c0d2-45bf-999d-e92fc49a4a89
1 drug(s) with this SPL Set ID
Sumatriptan nasal spray, USP contains sumatriptan USP, a selective 5-HT 1B/1D receptor agonist. Sumatriptan is chemically designated as 3-[2-(dimethylamino)ethyl]-N-methyl-indole-5-methanesulfonamide, and it has the following structure: The empirical formula is C 14 H 21 N 3 O 2 S, representing a molecular weight of 295.4. Sumatriptan USP is a white to pale yellow powder that is very slightly soluble in water. Each sumatriptan nasal spray, USP contains 20 mg of sumatriptan USP in a 100- mcL unit dose aqueous buffered solution containing monobasic potassium phosphate NF, anhydrous dibasic sodium phosphate USP, sulfuric acid NF, sodium hydroxide NF, and purified water USP. The pH of the solution is approximately 5.5. The osmolality of the solution is 742 mOsmol for 20-mg sumatriptan nasal spray. API structure