SPL Set ID: 4f5f8f2b-7200-4d76-9049-11dbc6cbd2ca
1 drug(s) with this SPL Set ID
Febuxostat is a xanthine oxidase inhibitor. The active ingredient in febuxostat is 2-[3-cyano-4-(2-methylpropoxy) phenyl]-4-methylthiazole-5-carboxylic acid, with a molecular weight of 316.38. The empirical formula is C 16 H 16 N 2 O 3 S. The chemical structure is: Febuxostat is a non-hygroscopic, white crystalline powder that is freely soluble in dimethylformamide; soluble in dimethylsulfoxide; sparingly soluble in ethanol; slightly soluble in methanol and acetonitrile; and practically insoluble in water. The melting range is 205 o C to 208 o C. Febuxostat tablets for oral use contain the active ingredient, febuxostat, and are available in two dosage strengths, 40 mg and 80 mg. Inactive ingredients include hydroxypropyl cellulose, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and sodium croscarmellose. Febuxostat tablets are coated with Opadry II, green which contains FD&C blue #2/indigo carmine aluminum lake, iron oxide yellow, macrogol, polyvinyl alcohol-part. hydrolyzed, talc, and titanium dioxide. chemical structure