SPL Set ID: 4cdcccda-7b9a-49d0-ac50-f4605a3c0ebe

Bevacizumab-adcd is a vascular endothelial growth factor inhibitor. Bevacizumab-adcd is a recombinant humanized monoclonal IgG1 antibody that contains human framework regions and murine complementarity-determining regions. Bevacizumab-adcd has an approximate molecular weight of 149 kDa. Bevacizumab-adcd is produced in a mammalian cell (Chinese Hamster Ovary) expression system. VEGZELMA (bevacizumab-adcd) injection is a sterile, preservative-free, clear to opalescent, colorless to pale brown solution in a single-dose vial for intravenous use. VEGZELMA contains bevacizumab-adcd at a concentration of 25 mg/mL in either 100 mg/4 mL or 400 mg/16 mL single-dose vials. Each mL of solution contains 25 mg bevacizumab-adcd, dibasic sodium phosphate (1.2 mg), monobasic sodium phosphate (5 mg), polysorbate 20 (0.4 mg), trehalose (54.3 mg), and Water for Injection, USP. The pH is 6.2.