SPL Set ID: 4cb78f66-6ccf-4ac7-8599-e199f6995f05

Dihydroergotamine mesylate is ergotamine hydrogenated in the 9,10 position as the mesylate salt. Dihydroergotamine mesylate is known chemically as ergotaman-3', 6', 18-trione, 9,10-dihydro-12'-hydroxy-2'-methyl-5'- (phenylmethyl)-, (5'α)-, monomethane-sulfonate. Its molecular weight is 679.78 and its empirical formula is C 33 H 37 N 5 O 5 •CH 4 O 3 S. The chemical structure is: Dihydroergotamine mesylate nasal spray is provided for intranasal administration as a clear, colorless to light yellow aqueous solution in an amber glass vial containing: dihydroergotamine mesylate.......................................................................... ..4 mg caffeine, anhydrous......................................................................................... 10 mg dextrose, anhydrous ....................................................................................... 50 mg carbon dioxide......................................................................................................qs purified water............................................................................................... qs 1 mL Each milliliter contains Dihydroergotamine mesylate……4 mg (equivalent to 3.43 mg dihydroergotamine) image description