SPL Set ID: 4bf239bb-c467-4add-b7cf-ea666e4fc693
1 drug(s) with this SPL Set ID
Denosumab-bbdz is a human IgG2 monoclonal antibody with affinity and specificity for human RANKL (receptor activator of nuclear factor kappa-B ligand). Denosumab-bbdz has an approximate molecular weight of 147 kDa and is produced in genetically engineered mammalian (Chinese hamster ovary) cells. Jubbonti (denosumab-bbdz) injection is a sterile, preservative-free, clear to slightly opalescent and colorless to slightly yellowish to slightly brownish solution for subcutaneous use. Each single-dose prefilled syringe contains 1 mL solution of 60 mg denosumab-bbdz, glacial acetic acid (1.021 mg), polysorbate 20 (0.1 mg), sodium hydroxide (0.499 mg), sorbitol (47 mg), and Water for Injection (USP). Hydrochloric acid and sodium hydroxide may be added to adjust the pH to 5.2.