SPL Set ID: 44b0c461-47fb-4106-ba11-6ed85530235c
1 drug(s) with this SPL Set ID
TABLOID brand Thioguanine was synthesized and developed by Hitchings, Elion, and associates at the Wellcome Research Laboratories. It is one of a large series of purine analogues which interfere with nucleic acid biosynthesis and has been found active against selected human neoplastic diseases. Thioguanine, known chemically as 2-amino-1,7-dihydro-6 H -purine-6-thione, is an analogue of the nucleic acid constituent guanine, and is closely related structurally and functionally to PURINETHOL ® (mercaptopurine). Its structural formula is: TABLOID brand Thioguanine is available in tablets for oral administration. Each scored tablet contains 40 mg thioguanine and the inactive ingredients acacia, lactose monohydrate, magnesium stearate, potato starch, and stearic acid. thioguanine chemical structure