SPL Set ID: 438c3d28-8bed-50f0-e063-6394a90a18e4
1 drug(s) with this SPL Set ID
The active ingredient of Ondansetron Injection, USP is ondansetron hydrochloride, USP a selective blocking agent of the serotonin 5-HT 3 receptor type. Its chemical name is (±) 1, 2, 3, 9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one, monohydrochloride, dihydrate. It has the following structural formula: The empirical formula is C 18 H 19 N 3 O•HCl•2H 2 O, representing a molecular weight of 365.9 g/mol. Ondansetron HCl, USP is a white to off-white powder that is soluble in water and normal saline. Each 1 mL of aqueous solution in the 2 mL single-dose vial contains Active: ondansetron 2 mg as ondansetron hydrochloride dihydrate; Inactives: sodium chloride 9.0 mg, USP; citric acid monohydrate 0.5 mg, USP; 0.25 mg sodium citrate dihydrate, USP and Water for Injection, USP q.s. Each 1 mL of aqueous solution in the 20 mL multidose vial contains Active: ondansetron 2 mg as ondansetron hydrochloride dihydrate; Preservatives: methylparaben 1.2 mg, NF and propylparaben 0.15 mg, NF; Inactives: sodium chloride 8.3 mg, USP; citric acid monohydrate 0.5 mg, USP; sodium citrate dihydrate 0.25 mg, USP and Water for Injection, USP q.s. Ondansetron Injection, USP is a clear, colorless, nonpyrogenic, sterile solution. The pH of the injection solution is 3.3 to 4.0. image description