SPL Set ID: 3e196aa4-0b01-44db-9267-98a995b54743

1 drug(s) with this SPL Set ID

Open DailyMed details

Marcaine BUPIVACAINE HYDROCHLORIDE AND EPINEPHRINE BITARTRATE
SEPTODONT, INC. FDA Rx Only

Bupivacaine hydrochloride is (±) -1-Butyl-2´, 6´-pipecoloxylidide monohydrochloride, monohydrate, a white crystalline powder that is freely soluble in 95 percent ethanol, soluble in water, and slightly soluble in chloroform or acetone. It has the following structural formula: Molecular Weight - 342.90 C 18 H 28 N 2 O • HCl • H 2 O Epinephrine bitartrate is (-)-1-(3,4-Dihydroxyphenyl)-2-methylamino-ethanol (+) tartrate (1:1) salt. It has the following structural formula: Molecular Weight - 333.29 C 13 H 19 NO 9 Bupivacaine is available in a sterile isotonic solution with epinephrine 1:200,000 (as bitartrate). Solutions of bupivacaine containing epinephrine may not be autoclaved. Bupivacaine is related chemically and pharmacologically to the aminoacyl local anesthetics. It is a homologue of mepivacaine and is chemically related to lidocaine. All three of these anesthetics contain an amide linkage between the aromatic nucleus and the amino or piperidine group. They differ in this respect from the procaine-type local anesthetics, which have an ester linkage. molecular structure molecular structure

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