SPL Set ID: 3c811e3e-f685-4af7-a4d1-037f2613ee68
1 drug(s) with this SPL Set ID
Ritonavir is an inhibitor of HIV protease with activity against the Human Immunodeficiency Virus (HIV). Ritonavir, USP is chemically designated as 2, 4, 7, 12-Tetraazatridecan-13-oic acid,10-hydroxy-2-methyl-5-(1-methylethyl)-1-[2-(1-methylethyl)-4-thiazolyl]-3,6-dioxo-8,11- bis(phenylmethyl)-5-thiazolymethyl ester [5S-(5R*,8R*,10R*,11R*)]. Its molecular formula is C 37 H 48 N 6 O 5 S 2 , and its molecular weight is 720.94. Ritonavir has the following structural formula: Ritonavir, USP is a white to off-white powder. It is freely soluble in methanol, methylene chloride, very slightly soluble in acetonitrile and practically insoluble in water. Ritonavir tablets, USP are available for oral administration in a strength of 100 mg ritonavir with the following inactive ingredients: colloidal silicon dioxide, copovidone, dibasic calcium phosphate anhydrous, sodium stearyl fumarate and sorbitan monolaurate. The tablets are coated with Opadry White which contains colloidal anhydrous silica, hydroxypropyl cellulose, hypromellose, polyethylene glycol, polysorbate 80, talc, and titanium dioxide.