SPL Set ID: 3b1e1cf1-ebd2-4aba-a219-9f9939fdb03b
1 drug(s) with this SPL Set ID
Minocycline hydrochloride, a semi synthetic derivative of tetracycline, is [ 4S -(4α,4aα,5aα,12aα)]-4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide mono hydrochloride. The structural formula is represented below: Minocycline hydrochloride extended-release tablets USP for oral administration contain minocycline hydrochloride USP equivalent to 45 mg, 55 mg, 90 mg or 135 mg of minocycline. In addition, 45 mg, 55 mg, 90 mg, and 135 mg tablets contain the following inactive ingredients: colloidal silicon dioxide, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol and titanium dioxide. The 45 mg tablets also contain iron oxide red, 55 mg tablets also contain D&C yellow # 10, FD&C blue # 1, FD&C red #40 and polysorbate 80, the 90 mg tablets also contain iron oxide yellow and talc, and 135 mg tablets also contain iron oxide red and iron oxide yellow. Drug Product meets USP Dissolution Test 3. Minocycline Hydrochloride