SPL Set ID: 35d28979-36b1-4630-b85e-a44e0a443734

Inderal ® LA (propranolol hydrochloride) is a synthetic beta-adrenergic receptor-blocking agent chemically described as 2-Propanol, 1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-, hydrochloride,(±)-. Its molecular and structural formulae are: C 16 H 21 NO 2 · HCl Propranolol hydrochloride USP is a stable, white, crystalline solid which is readily soluble in water and ethanol. Its molecular weight is 295.80. Inderal LA is formulated to provide a sustained release of propranolol hydrochloride USP. Inderal LA is available as 60 mg, 80 mg, 120 mg, and 160 mg capsules for oral administration. • Each Inderal LA 60 mg capsule contains 60 mg propranolol hydrochloride USP (equivalent to 52.60 mg of propranolol). • Each Inderal LA 80 mg capsule contains 80 mg propranolol hydrochloride USP (equivalent to 70.14 mg of propranolol). • Each Inderal LA 120 mg capsule contains 120 mg propranolol hydrochloride USP (equivalent to 105.21 mg of propranolol). • Each Inderal LA 160 mg capsule contains 160 mg propranolol hydrochloride USP (equivalent to 140.28 mg of propranolol). The inactive ingredients contained in Inderal LA capsules are: diethyl phthalate, hypromellose phthalate, ethylcellulose, povidone, polyethylene glycol, corn starch, sucrose, hypromellose, gelatin capsules and titanium dioxide. In addition Inderal LA 60 mg capsules contain D&C Red No. 28 and FD&C Blue No. 1; Inderal LA 80 mg and 120 mg capsules contain FD&C Red No. 3 and FD&C Blue No. 1; Inderal LA 160 mg capsules contain FD&C Blue No. 1. FDA approved dissolution specifications differ from USP. inderal-la-01