SPL Set ID: 34bef49c-eca1-4f17-9b1b-55900ac40829

Celecoxib capsule is a nonsteroidal anti-inflammatory drug, available as capsules containing 50 mg, 100 mg, 200 mg and 400 mg celecoxib USP for oral administration. The chemical name is 4-[5-(4-methylphenyl)- 3-(trifluoromethyl)-1H-pyrazol-1-yl] benzenesulfonamide and is a diaryl-substituted pyrazole. The molecular weight is 381.38. Its molecular formula is C 17 H 14 F 3 N 3 O 2 S, and it has the following chemical structure: Celecoxib is a white or almost white crystalline powder with a pKa of 11.1 (sulfonamide moiety). Celecoxib is soluble to freely soluble in ethanol, soluble in methylene chloride and practically insoluble in water. The inactive ingredients in celecoxib capsules include: crospovidone, hydroxypropyl cellulose, lactose monohydrate, povidone, sodium lauryl sulfate, sodium stearyl fumarate. The empty hard gelatin capsule shells contain gelatin and titanium dioxide. The capsules are imprinted with edible ink containing propylene glycol and shellac. In addition, 50 mg capsules are imprinted with FD&C Red #40 aluminum lake and sodium hydroxide. 100 mg capsules are imprinted with FD & C Blue # 2 aluminum lake and strong ammonia solution. 200 mg capsules are imprinted with strong ammonia solution and yellow iron oxide. 400 mg capsules are imprinted with FD & C Blue # 2 aluminum lake, strong ammonia solution and yellow iron oxide. Chemical Structure