SPL Set ID: 348eadb6-5be2-f8c7-e063-6394a90a1314
1 drug(s) with this SPL Set ID
Levocetirizine dihydrochloride, the active component of Levocetirizine Dihydrochloride Tablets, USP is an orally active H 1 -receptor antagonist. The chemical name is (-)2-[2-[4-[(4-chlorophenyl) phenyl methyl] piperazin-1-yl] ethoxy] acetic acid dihydrochloride. Levocetirizine dihydrochloride is the R enantiomer of cetirizine hydrochloride, a racemic compound with antihistaminic properties. The empirical formula of levocetirizine dihydrochloride is C 21 H 25 C1N 2 O 3 •2HCl. The molecular weight is 461.81 g/mol and the chemical structure is shown below: Levocetirizine dihydrochloride is a white to off white crystalline powder and soluble in methanol and in water. Levocetirizine Dihydrochloride Tablets, USP, 5 mg are formulated as immediate release, white, oval, film-coated, biconvex tablets, one side embossed with ‘G’ breakline ‘G’ and the other side plain for oral administration. Inactive ingredients are: colloidal silicon dioxide, lactose monohydrate, magnesium stearate and microcrystalline cellulose. The film coating contains hypromellose, macrogol 400, and titanium dioxide. structure