SPL Set ID: 32769721-c1dd-4bd3-90aa-a6cab59d3cd6

Ticagrelor tablets contains ticagrelor, a cyclopentyltriazolopyrimidine, inhibitor of platelet activation and aggregation mediated by the P2Y 12 ADP-receptor. Chemically it is (1S,2S,3 R ,5S)-3-[7-{[(1 R ,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino}-5(propylthio)-3 H -[1,2,3]-triazolo[4,5- d ]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol. The empirical formula of ticagrelor is C 23 H 28 F 2 N 6 O 4 S and its molecular weight is 522.57. The chemical structure of ticagrelor is: Ticagrelor is a crystalline powder with an aqueous solubility of approximately 10 μg/mL at room temperature Ticagrelor 90 mg tablets for oral administration contain 90 mg of ticagrelor and the following ingredients: mannitol, microcrystalline cellulose, sodium starch glycolate, povidone, magnesium stearate, hydroxypropyl methylcellulose, polyethylene glycol 400, talc, titanium dioxide, and yellow iron oxide. Ticagrelor 60 mg tablets for oral administration contain 60 mg of ticagrelor and the following ingredients: mannitol, microcrystalline cellulose, sodium starch glycolate, povidone, magnesium stearate, hydroxypropyl methylcellulose, polyethylene glycol 400, talc, titanium dioxide, black iron oxide, and red iron oxide. str