SPL Set ID: 303bc1e6-0735-4ea1-84cd-6c1b621de0ed
1 drug(s) with this SPL Set ID
Phenylephrine is an alpha-1 adrenergic receptor agonist. Phenylephrine Hydrochloride Injection USP, 10 mg/mL, is a clear, colorless, sterile, nonpyrogenic, aqueous solution for intravenous use. It must be diluted before administration as an intravenous bolus or continuous intravenous infusion. The chemical name of phenylephrine hydrochloride is (-)- m -hydroxy-α-[(methylamino)methyl]benzyl alcohol hydrochloride and is chemically designated as C 9 H 14 ClNO 2 with a molecular weight of 203.67 g/mol. Its structural formula is depicted below: Phenylephrine hydrochloride USP is white or practically white powder. Phenylephrine hydrochloride is soluble in water, and ethanol, and insoluble in chloroform and ethyl ether. Phenylephrine Hydrochloride Injection USP, 10 mg/mL, is sensitive to light. Each mL contains: phenylephrine hydrochloride USP, 10 mg; sodium chloride 3.5 mg; sodium citrate dihydrate 4 mg; citric acid monohydrate 1 mg; and sodium metabisulfite 2 mg in water for injection. The pH is adjusted with sodium hydroxide and/or hydrochloric acid if necessary. The pH range is 3.5 to 5.5. Phenylephrine Hydrochloride Chemical Structure