SPL Set ID: 2d7b6e7d-cf01-70a2-e063-6394a90afbe6
1 drug(s) with this SPL Set ID
Cimetidine is a histamine H 2 -receptor antagonist. Chemically it is N" -cyano- N -methyl- N' -[2-[[(5-methyl-1 H -imidazol-4-yl)methyl]thio]-ethyl]guanidine. Its structural formula is: Cimetidine contains an imidazole ring, and is chemically related to histamine. Cimetidine, USP is a white to off-white, crystalline powder. Structural Formula Solubility Characteristics Cimetidine, USP is freely soluble in methanol, soluble in alcohol and in polyethylene glycol 400, sparingly soluble in isopropyl alcohol, slightly soluble in water and in chloroform, and practically insoluble in ether. Each film-coated tablet, for oral administration, contains 200 mg, 300 mg, 400 mg, and 800 mg cimetidine, USP. Inactive ingredients are: corn starch, D&C yellow no. 10 aluminum lake, FD&C blue no. 1 aluminum lake, FD&C yellow no. 6 aluminum lake, hypromellose, lecithin, magnesium stearate, microcrystalline cellulose, polydextrose, polyethylene glycol, povidone, sodium alginate, sodium lauryl sulfate, sodium starch glycolate, titanium dioxide, triacetin, and vanillin.