SPL Set ID: 2d569c8a-844b-44a8-81df-3f9c9300a79c

Zonisamide Capsules USP, are an antiseizure drug chemically classified as a sulfonamide and unrelated to other antiseizure agents. The active ingredient is zonisamide, 1,2 -benzisoxazole-3-methanesulfonamide. The empirical formula is C 8 H 8 N 2 O 3 S with a molecular weight of 212.23. Zonisamide is a white to off white powder, pKa = 10.6, and is freely soluble in dimethyl formamide, soluble in methanol. The chemical structure is: Zonisamide Capsules USP, are supplied for oral administration as capsules containing 25 mg, 50 mg or 100 mg zonisamide. Each capsule contains the labeled amount of zonisamide plus the following inactive ingredients: hydrogenated vegetable oil, microcrystalline cellulose, colloidal silicon dioxide, sodium lauryl sulfate, gelatin and titanium dioxide. Additionally the 50 mg contains D&C Red No. 28 and FD&C Blue No. 1 and the 100 mg contains FD&C Red No. 40. The black imprinting ink contains shellac, propylene glycol, black iron oxide and potassium hydroxide.