SPL Set ID: 29140df2-24a3-4a6f-a8e3-065521448d61

Denosumab-mobz is a human IgG2 monoclonal antibody with affinity and specificity for human RANKL (receptor activator of nuclear factor kappa-B ligand). Denosumab-mobz has an approximate molecular weight of 147 kDa and is produced in genetically engineered mammalian (Chinese hamster ovary) cells. Boncresa(denosumab-mobz) injection is a sterile, preservative-free, clear, colorless to pale yellow solution for subcutaneous use. Each single-dose prefilled syringe contains 1 mL solution of 60 mg denosumab-mobz (60 mg/mL solution), glacial acetic acid (1 mg), polysorbate 20 (0.1 mg), sorbitol (46 mg), Water for Injection (USP), and sodium hydroxide to adjust the pH to 5.2.