SPL Set ID: 2609da8f-80dc-448e-8eba-35d11488ce7f

Methotrexate is dihydrofolate reductase inhibitor with the chemical name of L-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-,disodium salt (9CI). The molecular formula is C 20 H 22 N 8 O 5 Na 2 and the molecular weight is 498.40 g/mol. The structural formula is: Methotrexate Tablets, USP for oral use is available in bottles of 36 tablets. Each methotrexate tablet contains 2.5 mg methotrexate equivalent to 2.74 mg methotrexate disodium and the following inactive ingredients: lactose monohydrate, magnesium stearate and pregelatinized starch (maize). Chemical Structure