SPL Set ID: 201fdedf-1736-4e52-9d7d-de14292547fd
1 drug(s) with this SPL Set ID
Naloxone Hydrochloride Injection, USP, an opioid antagonist, is a synthetic congener of oxymorphone. In structure it differs from oxymorphone in that the methyl group on the nitrogen atom is replaced by an allyl group. Naloxone hydrochloride occurs as a white to slightly off-white powder, and is soluble in water, in dilute acids, and in strong alkali; slightly soluble in alcohol; practically insoluble in ether and in chloroform. Naloxone Hydrochloride Injection is available as a sterile solution for intravenous, intramuscular and subcutaneous administration in two concentrations: 0.4 mg and 1 mg of naloxone hydrochloride per mL. pH is adjusted to 3.5 ± 0.5 with hydrochloric acid. The 0.4 mg/mL prefilled syringe is available in an unpreserved, paraben-free formulation containing 9 mg/mL of sodium chloride. The 1 mg/mL prefilled syringe is available in an unpreserved, paraben-free formulation containing 9 mg/mL of sodium chloride. nalox-struc-01.jpg