SPL Set ID: 1e671632-d5bd-499a-ba06-0d1dc0d99622
1 drug(s) with this SPL Set ID
Rufinamide is a triazole derivative structurally unrelated to currently marketed antiepileptic drugs (AEDs). Rufinamide has the chemical name 1-[(2, 6-difluorophenyl) methyl]-1 H -1, 2, 3-triazole-4 carboxamide. It has an empirical formula of C 10 H 8 F 2 N 4 O and a molecular weight of 238.2. The drug substance is a white, crystalline, powder. Rufinamide is practically insoluble in water, slightly soluble in dimethylsulphoxide, tetrahydrofuran and in methanol, and very slightly soluble in ethanol and in acetonitrile. Rufinamide is available for oral administration as a liquid containing rufinamide at a concentration of 40 mg/mL. Inactive ingredients include Citric acid anhydrous, colloidal silicon dioxide , hydroxy ethyl cellulose, methyl paraben, microcrystalline cellulose/ carboxymethyl cellulose sodium, non-crystallizing sorbitol solution, orange juice, poloxamer 188, potassium sorbate, propyl paraben, propylene glycol, simethicone emulsion. description