SPL Set ID: 1e566c10-4498-4f79-8874-4cc8c4216213

Metolazone tablets, USP, for oral administration contain 2½, 5, or 10 mg of metolazone, USP, a diuretic/saluretic/antihypertensive drug of the quinazoline class. Metolazone has the molecular formula C 16 H 16 ClN 3 O 3 S, the chemical name 7-chloro-1, 2, 3, 4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-6-quinazolinesulfonamide, and a molecular weight of 365.83. The structural formula is: Metolazone is only sparingly soluble in methanol and insoluble in water. Inactive Ingredients: colloidal silicon dioxide, magnesium stearate, microcrystalline cellulose, iron oxide red and iron oxide yellow. Structure