SPL Set ID: 1d04e17d-7399-430a-a8bb-fa1912b155e9
1 drug(s) with this SPL Set ID
Avanafil is a selective inhibitor of cGMP-specific PDE5. Avanafil is designated chemically as (S)-4-[(3-Chloro-4-methoxybenzyl)amino]-2-[2-(hydroxymethyl)-1-pyrrolidinyl]- N -(2-pyrimidinylmethyl)-5-pyrimidinecarboxamide and has the following structural formula: Avanafil occurs as an off-white to white powder, molecular formula C 23 H 26 ClN 7 O 3 and molecular weight of 483.95 and is slightly soluble in methanol, ethanol and insoluble in water. Avanafil tablets, for oral administration, is supplied as oval, white to off-white tablets containing 50 mg, 100 mg, or 200 mg avanafil. In addition to the active ingredient, avanafil, each tablet contains the following inactive ingredients: fumaric acid, hydroxyl propyl cellulose, low- substituted hydroxyl propyl cellulose, magnesium stearate, mannitol and sodium bicarbonate. avanafil-structure