SPL Set ID: 1cf9b6dd-9d4e-4ea1-95ae-e9e46a3d1b20

1 drug(s) with this SPL Set ID

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ISOSORBIDE DINITRATE ISOSORBIDE DINITRATE
PROFICIENT RX LP FDA Rx Only

Isosorbide dinitrate (ISDN) is 1,4:3,6-dianhydro-D-glucitol 2,5-dinitrate, an organic nitrate whose structural formula is and whose molecular weight is 236.14. The organic nitrates are vasodilators, active on both arteries and veins. Isosorbide dinitrate is a white, crystalline powder compound which is stable in air and in solution, has a melting point of 69°C to 72°C and optically active. Isosorbide dinitrate is very soluble in acetone, sparingy soluble in alcohol and very slightly soluble in water. Each Isosorbide dinitrate tablet contains 20 mg of isosorbide dinitrate. The inactive ingredients in each tablet are microcrystalline cellulose, colloidal silicon dioxide, and magnesium stearate. The 20 mg dosage strength also contains anhydrous lactose and sodium starch glycolate Type A. Additionally 20mg contains FD & C Blue 1 Al lake and D & C Yellow 10 Al lake. FDA approved dissolution test specifications differ from USP. Isosorbide Dinitrate Chemical Structure

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