SPL Set ID: 1c2f9bf2-1711-4975-af02-32614db25add
1 drug(s) with this SPL Set ID
Rufinamide is a triazole derivative structurally unrelated to currently marketed antiepileptic drugs (AEDs). Rufinamide has the chemical name 1-[(2,6-Difluorophenyl)methyl]-1H-1,2,3-triazole-4-carboxamide. It has an empirical formula of C 10 H 8 F 2 N 4 O and a molecular weight of 238.19. The drug substance is a white, crystalline neutral powder. Rufinamide is slightly soluble in tetrahydrofuran and in methanol, very slightly soluble in alcohol and in acetonitrile, practically insoluble in water. Rufinamide is available for oral administration as a liquid containing rufinamide USP at a concentration of 40 mg/mL. Inactive ingredients include anhydrous citric acid, hydroxyethyl cellulose, methyl paraben, microcrystalline cellulose and carboxymethyl cellulose sodium, orange flavor, poloxamer, potassium sorbate, propylene glycol, propyl paraben, purified water, simethicone emulsion and sorbitol. rufinamideoschemicalstructure