SPL Set ID: 15b87f7f-1abf-4d8a-bdbe-03bea0021a68
1 drug(s) with this SPL Set ID
The active ingredient in famotidine tablets, USP is a histamine-2 (H 2 ) receptor antagonist. Famotidine is 3-[({2-[(diaminomethylidene) amino]-1, 3-thiazol-4-yl} methyl) sulfanyl]-N- sulfamoyl propanimidamide. The molecular formula of famotidine is C 8 H 15 N 7 O 2 S 3 and its molecular weight is 337.45 g/mol. Its structural formula is: Each famotidine tablet for oral administration contains either 20 mg or 40 mg of famotidine USP and the following inactive ingredients: corn starch, hypromellose, magnesium stearate, microcrystalline cellulose, sodium starch glycolate, opadry white and opadry yellow. The opadry white contains hypromellose, hydroxypropyl cellulose, titanium dioxide, talc and carnauba wax. In addition, the 20 mg tablets contain red iron oxide, and yellow iron oxide. Famotidine USP is a White to pale yellowish-white, crystalline powder that is Freely soluble in dimethyl formamide, freely soluble in glacial acetic acid, slightly soluble in methanol, very slightly soluble in water, practically insoluble in acetone, practically insoluble in alcohol, practically insoluble in chloroform, practically insoluble in ether & practically insoluble in ethyl acetate. FDA approved dissolution test specifications differ from USP. Image