nyquil vapocool severe cold and flu plus congestion

Generic: acetaminophen, dextromethorphan hydrobromide, doxylamine succinate, and phenylephrine hydrochloride

Labeler: the procter & gamble manufacturing company
NDC Directory HUMAN OTC DRUG OTC MONOGRAPH DRUG Inactive Finished

Drug Facts

Product Profile

Brand Name nyquil vapocool severe cold and flu plus congestion
Generic Name acetaminophen, dextromethorphan hydrobromide, doxylamine succinate, and phenylephrine hydrochloride
Labeler the procter & gamble manufacturing company
Dosage Form SOLUTION
Routes
ORAL
Active Ingredients

acetaminophen 650 mg/30mL, dextromethorphan hydrobromide 20 mg/30mL, doxylamine succinate 12.5 mg/30mL, phenylephrine hydrochloride 10 mg/30mL

Manufacturer
The Procter & Gamble Manufacturing Company

Identifiers & Regulatory

Product NDC 69423-989
Product ID 69423-989_402e2e59-c1b6-8c3c-e063-6294a90a9615
Product Type HUMAN OTC DRUG
Marketing Category OTC MONOGRAPH DRUG
Application Number M012
Listing Expiration 2026-12-31
Marketing Start 2021-03-22

Pharmacologic Class

Classes
adrenergic alpha1-agonists [moa] antihistamine [epc] histamine receptor antagonists [moa] sigma-1 agonist [epc] sigma-1 receptor agonists [moa] uncompetitive n-methyl-d-aspartate receptor antagonist [epc] uncompetitive nmda receptor antagonists [moa] alpha-1 adrenergic agonist [epc]

Normalized Code Variants

Searchable formats for this product NDC code

Digits Only 69423989
Hyphenated Format 69423-989

Supplemental Identifiers

RxCUI
1431245
UPC
0323900039414
UNII
362O9ITL9D 9D2RTI9KYH V9BI9B5YI2 04JA59TNSJ

Packaging Origin

Original Packager
true

Resolved Product View

Precedence rule: structured NDC data is preferred, falling back to linked label metadata when unavailable. Source tags show the origin of each value.

Resolved Identity

Brand Name nyquil vapocool severe cold and flu plus congestion (source: ndc)
Generic Name acetaminophen, dextromethorphan hydrobromide, doxylamine succinate, and phenylephrine hydrochloride (source: ndc)
Application Number M012 (source: ndc)
Routes
ORAL
source: ndc

Resolved Composition

Strengths
  • 650 mg/30mL
  • 20 mg/30mL
  • 12.5 mg/30mL
  • 10 mg/30mL
source: ndc
Packaging
  • 236 mL in 1 BOTTLE, PLASTIC (69423-989-08)
  • 354 mL in 1 BOTTLE, PLASTIC (69423-989-12)
source: ndc

Packages (2)

69423-989-08 236 mL in 1 BOTTLE, PLASTIC (69423-989-08) 69423-989-12 354 mL in 1 BOTTLE, PLASTIC (69423-989-12)

Ingredients (4)

acetaminophen (650 mg/30mL) dextromethorphan hydrobromide (20 mg/30mL) doxylamine succinate (12.5 mg/30mL) phenylephrine hydrochloride (10 mg/30mL)

Linked Drug Pages (1)

NyQuil VapoCOOL SEVERE COLD and FLU plus CONGESTION ndc-match (0.9)

Raw FDA Data

View complete raw FDA NDC JSON payload 
{"route": ["ORAL"], "spl_id": "402e2e59-c1b6-8c3c-e063-6294a90a9615", "openfda": {"upc": ["0323900039414"], "unii": ["362O9ITL9D", "9D2RTI9KYH", "V9BI9B5YI2", "04JA59TNSJ"], "rxcui": ["1431245"], "spl_set_id": ["ef6df67c-0afa-4825-e053-2995a90aced9"], "manufacturer_name": ["The Procter & Gamble Manufacturing Company"], "is_original_packager": [true]}, "finished": true, "packaging": [{"sample": false, "description": "236 mL in 1 BOTTLE, PLASTIC (69423-989-08)", "package_ndc": "69423-989-08", "marketing_start_date": "20210322"}, {"sample": false, "description": "354 mL in 1 BOTTLE, PLASTIC (69423-989-12)", "package_ndc": "69423-989-12", "marketing_start_date": "20210322"}], "brand_name": "NyQuil VapoCOOL SEVERE COLD and FLU plus CONGESTION", "product_id": "69423-989_402e2e59-c1b6-8c3c-e063-6294a90a9615", "dosage_form": "SOLUTION", "pharm_class": ["Adrenergic alpha1-Agonists [MoA]", "Antihistamine [EPC]", "Histamine Receptor Antagonists [MoA]", "Sigma-1 Agonist [EPC]", "Sigma-1 Receptor Agonists [MoA]", "Uncompetitive N-methyl-D-aspartate Receptor Antagonist [EPC]", "Uncompetitive NMDA Receptor Antagonists [MoA]", "alpha-1 Adrenergic Agonist [EPC]"], "product_ndc": "69423-989", "generic_name": "acetaminophen, dextromethorphan hydrobromide, doxylamine succinate, and phenylephrine hydrochloride", "labeler_name": "The Procter & Gamble Manufacturing Company", "product_type": "HUMAN OTC DRUG", "brand_name_base": "NyQuil VapoCOOL SEVERE", "brand_name_suffix": "COLD and FLU plus CONGESTION", "active_ingredients": [{"name": "ACETAMINOPHEN", "strength": "650 mg/30mL"}, {"name": "DEXTROMETHORPHAN HYDROBROMIDE", "strength": "20 mg/30mL"}, {"name": "DOXYLAMINE SUCCINATE", "strength": "12.5 mg/30mL"}, {"name": "PHENYLEPHRINE HYDROCHLORIDE", "strength": "10 mg/30mL"}], "application_number": "M012", "marketing_category": "OTC MONOGRAPH DRUG", "marketing_start_date": "20210322", "listing_expiration_date": "20261231"}