alka-seltzer original

Generic: anhydrous citric acid, aspirin, and sodium bicarbonate

Labeler: bayer healthcare llc.
NDC Directory HUMAN OTC DRUG OTC MONOGRAPH DRUG Inactive Finished

Drug Facts

Product Profile

Brand Name alka-seltzer original
Generic Name anhydrous citric acid, aspirin, and sodium bicarbonate
Labeler bayer healthcare llc.
Dosage Form TABLET, EFFERVESCENT
Routes
ORAL
Active Ingredients

anhydrous citric acid 1000 mg/1, aspirin 325 mg/1, sodium bicarbonate 1916 mg/1

Manufacturer
Bayer HealthCare LLC.

Identifiers & Regulatory

Product NDC 0280-4000
Product ID 0280-4000_4526b5f2-3b6b-b295-e063-6294a90ae6c1
Product Type HUMAN OTC DRUG
Marketing Category OTC MONOGRAPH DRUG
Application Number M013
Listing Expiration 2026-12-31
Marketing Start 2010-03-02

Pharmacologic Class

Established (EPC)
calculi dissolution agent [epc] anti-coagulant [epc] nonsteroidal anti-inflammatory drug [epc] platelet aggregation inhibitor [epc]
Mechanism of Action
acidifying activity [moa] calcium chelating activity [moa] cyclooxygenase inhibitors [moa]
Chemical Structure
anti-inflammatory agents, non-steroidal [cs]
Physiologic Effect
decreased coagulation factor activity [pe] decreased prostaglandin production [pe] decreased platelet aggregation [pe]

Normalized Code Variants

Searchable formats for this product NDC code

Digits Only 02804000
Hyphenated Format 0280-4000

Supplemental Identifiers

RxCUI
1536675 1536680
UNII
XF417D3PSL R16CO5Y76E 8MDF5V39QO
NUI
N0000175833 N0000175835 N0000175980 N0000008556 N0000175089 N0000000160 N0000008836 M0001335 N0000175722 N0000175578 N0000008832

Packaging Origin

Original Packager
true

Resolved Product View

Precedence rule: structured NDC data is preferred, falling back to linked label metadata when unavailable. Source tags show the origin of each value.

Resolved Identity

Brand Name alka-seltzer original (source: ndc)
Generic Name anhydrous citric acid, aspirin, and sodium bicarbonate (source: ndc)
Application Number M013 (source: ndc)
Routes
ORAL
source: ndc

Resolved Composition

Strengths
  • 1000 mg/1
  • 325 mg/1
  • 1916 mg/1
source: ndc
Packaging
  • 6 POUCH in 1 CARTON (0280-4000-01) / 2 TABLET, EFFERVESCENT in 1 POUCH
  • 24 POUCH in 1 CARTON (0280-4000-02) / 2 TABLET, EFFERVESCENT in 1 POUCH
  • 18 POUCH in 1 CARTON (0280-4000-03) / 2 TABLET, EFFERVESCENT in 1 POUCH
  • 58 POUCH in 1 CARTON (0280-4000-04) / 2 TABLET, EFFERVESCENT in 1 POUCH
  • 36 POUCH in 1 CARTON (0280-4000-05) / 2 TABLET, EFFERVESCENT in 1 POUCH
  • 12 POUCH in 1 CARTON (0280-4000-06) / 2 TABLET, EFFERVESCENT in 1 POUCH
  • 26 POUCH in 1 CARTON (0280-4000-07) / 2 TABLET, EFFERVESCENT in 1 POUCH
source: ndc

Packages (7)

0280-4000-01 6 POUCH in 1 CARTON (0280-4000-01) / 2 TABLET, EFFERVESCENT in 1 POUCH 0280-4000-02 24 POUCH in 1 CARTON (0280-4000-02) / 2 TABLET, EFFERVESCENT in 1 POUCH 0280-4000-03 18 POUCH in 1 CARTON (0280-4000-03) / 2 TABLET, EFFERVESCENT in 1 POUCH 0280-4000-04 58 POUCH in 1 CARTON (0280-4000-04) / 2 TABLET, EFFERVESCENT in 1 POUCH 0280-4000-05 36 POUCH in 1 CARTON (0280-4000-05) / 2 TABLET, EFFERVESCENT in 1 POUCH 0280-4000-06 12 POUCH in 1 CARTON (0280-4000-06) / 2 TABLET, EFFERVESCENT in 1 POUCH 0280-4000-07 26 POUCH in 1 CARTON (0280-4000-07) / 2 TABLET, EFFERVESCENT in 1 POUCH

Ingredients (3)

anhydrous citric acid (1000 mg/1) aspirin (325 mg/1) sodium bicarbonate (1916 mg/1)

Linked Drug Pages (1)

Alka-Seltzer Original ndc-match (0.9)

Raw FDA Data

View complete raw FDA NDC JSON payload 
{"route": ["ORAL"], "spl_id": "4526b5f2-3b6b-b295-e063-6294a90ae6c1", "openfda": {"nui": ["N0000175833", "N0000175835", "N0000175980", "N0000008556", "N0000175089", "N0000000160", "N0000008836", "M0001335", "N0000175722", "N0000175578", "N0000008832"], "unii": ["XF417D3PSL", "R16CO5Y76E", "8MDF5V39QO"], "rxcui": ["1536675", "1536680"], "spl_set_id": ["5be36a7f-7d1f-468d-9c29-92c8cd3ef1bc"], "pharm_class_cs": ["Anti-Inflammatory Agents, Non-Steroidal [CS]"], "pharm_class_pe": ["Decreased Coagulation Factor Activity [PE]", "Decreased Prostaglandin Production [PE]", "Decreased Platelet Aggregation [PE]"], "pharm_class_epc": ["Calculi Dissolution Agent [EPC]", "Anti-coagulant [EPC]", "Nonsteroidal Anti-inflammatory Drug [EPC]", "Platelet Aggregation Inhibitor [EPC]"], "pharm_class_moa": ["Acidifying Activity [MoA]", "Calcium Chelating Activity [MoA]", "Cyclooxygenase Inhibitors [MoA]"], "manufacturer_name": ["Bayer HealthCare LLC."], "is_original_packager": [true]}, "finished": true, "packaging": [{"sample": false, "description": "6 POUCH in 1 CARTON (0280-4000-01)  / 2 TABLET, EFFERVESCENT in 1 POUCH", "package_ndc": "0280-4000-01", "marketing_start_date": "20121010"}, {"sample": false, "description": "24 POUCH in 1 CARTON (0280-4000-02)  / 2 TABLET, EFFERVESCENT in 1 POUCH", "package_ndc": "0280-4000-02", "marketing_start_date": "20121010"}, {"sample": false, "description": "18 POUCH in 1 CARTON (0280-4000-03)  / 2 TABLET, EFFERVESCENT in 1 POUCH", "package_ndc": "0280-4000-03", "marketing_start_date": "20121010"}, {"sample": false, "description": "58 POUCH in 1 CARTON (0280-4000-04)  / 2 TABLET, EFFERVESCENT in 1 POUCH", "package_ndc": "0280-4000-04", "marketing_start_date": "20121010"}, {"sample": false, "description": "36 POUCH in 1 CARTON (0280-4000-05)  / 2 TABLET, EFFERVESCENT in 1 POUCH", "package_ndc": "0280-4000-05", "marketing_start_date": "20121010"}, {"sample": false, "description": "12 POUCH in 1 CARTON (0280-4000-06)  / 2 TABLET, EFFERVESCENT in 1 POUCH", "package_ndc": "0280-4000-06", "marketing_start_date": "20220324"}, {"sample": false, "description": "26 POUCH in 1 CARTON (0280-4000-07)  / 2 TABLET, EFFERVESCENT in 1 POUCH", "package_ndc": "0280-4000-07", "marketing_start_date": "20121010"}], "brand_name": "Alka-Seltzer Original", "product_id": "0280-4000_4526b5f2-3b6b-b295-e063-6294a90ae6c1", "dosage_form": "TABLET, EFFERVESCENT", "pharm_class": ["Acidifying Activity [MoA]", "Alkalinizing Activity [MoA]", "Anti-Inflammatory Agents", "Non-Steroidal [CS]", "Anti-coagulant [EPC]", "Calcium Chelating Activity [MoA]", "Calculi Dissolution Agent [EPC]", "Cyclooxygenase Inhibitors [MoA]", "Decreased Coagulation Factor Activity [PE]", "Decreased Platelet Aggregation [PE]", "Decreased Prostaglandin Production [PE]", "Nonsteroidal Anti-inflammatory Drug [EPC]", "Platelet Aggregation Inhibitor [EPC]"], "product_ndc": "0280-4000", "generic_name": "ANHYDROUS CITRIC ACID, ASPIRIN, and SODIUM BICARBONATE", "labeler_name": "Bayer HealthCare LLC.", "product_type": "HUMAN OTC DRUG", "brand_name_base": "Alka-Seltzer Original", "active_ingredients": [{"name": "ANHYDROUS CITRIC ACID", "strength": "1000 mg/1"}, {"name": "ASPIRIN", "strength": "325 mg/1"}, {"name": "SODIUM BICARBONATE", "strength": "1916 mg/1"}], "application_number": "M013", "marketing_category": "OTC MONOGRAPH DRUG", "marketing_start_date": "20100302", "listing_expiration_date": "20261231"}