alka-seltzer extra strength

Generic: anhydrous citric acid, sodium bicarbonate, and aspirin

Labeler: bayer healthcare llc.
NDC Directory HUMAN OTC DRUG OTC MONOGRAPH DRUG Inactive Finished

Drug Facts

Product Profile

Brand Name alka-seltzer extra strength
Generic Name anhydrous citric acid, sodium bicarbonate, and aspirin
Labeler bayer healthcare llc.
Dosage Form GRANULE, EFFERVESCENT
Routes
ORAL
Active Ingredients

anhydrous citric acid 1000 mg/1, aspirin 500 mg/1, sodium bicarbonate 1985 mg/1

Manufacturer
Bayer HealthCare LLC.

Identifiers & Regulatory

Product NDC 0280-0211
Product ID 0280-0211_45266611-610c-a481-e063-6394a90a1bf0
Product Type HUMAN OTC DRUG
Marketing Category OTC MONOGRAPH DRUG
Application Number M001
Listing Expiration 2026-12-31
Marketing Start 2011-04-11

Pharmacologic Class

Established (EPC)
calculi dissolution agent [epc] anti-coagulant [epc] nonsteroidal anti-inflammatory drug [epc] platelet aggregation inhibitor [epc]
Mechanism of Action
acidifying activity [moa] calcium chelating activity [moa] cyclooxygenase inhibitors [moa]
Chemical Structure
anti-inflammatory agents, non-steroidal [cs]
Physiologic Effect
decreased coagulation factor activity [pe] decreased prostaglandin production [pe] decreased platelet aggregation [pe]

Normalized Code Variants

Searchable formats for this product NDC code

Digits Only 02800211
Hyphenated Format 0280-0211

Supplemental Identifiers

RxCUI
1872085 1872088
UPC
0016500044048
UNII
XF417D3PSL R16CO5Y76E 8MDF5V39QO
NUI
N0000175833 N0000175835 N0000175980 N0000008556 N0000175089 N0000000160 N0000008836 M0001335 N0000175722 N0000175578 N0000008832

Packaging Origin

Original Packager
true

Resolved Product View

Precedence rule: structured NDC data is preferred, falling back to linked label metadata when unavailable. Source tags show the origin of each value.

Resolved Identity

Brand Name alka-seltzer extra strength (source: ndc)
Generic Name anhydrous citric acid, sodium bicarbonate, and aspirin (source: ndc)
Application Number M001 (source: ndc)
Routes
ORAL
source: ndc

Resolved Composition

Strengths
  • 1000 mg/1
  • 500 mg/1
  • 1985 mg/1
source: ndc
Packaging
  • 12 PACKET in 1 CARTON (0280-0211-24) / 2 GRANULE, EFFERVESCENT in 1 PACKET
source: ndc

Packages (1)

0280-0211-24 12 PACKET in 1 CARTON (0280-0211-24) / 2 GRANULE, EFFERVESCENT in 1 PACKET

Ingredients (3)

anhydrous citric acid (1000 mg/1) aspirin (500 mg/1) sodium bicarbonate (1985 mg/1)

Linked Drug Pages (1)

Alka-Seltzer Extra Strength ndc-match (0.9)

Raw FDA Data

View complete raw FDA NDC JSON payload 
{"route": ["ORAL"], "spl_id": "45266611-610c-a481-e063-6394a90a1bf0", "openfda": {"nui": ["N0000175833", "N0000175835", "N0000175980", "N0000008556", "N0000175089", "N0000000160", "N0000008836", "M0001335", "N0000175722", "N0000175578", "N0000008832"], "upc": ["0016500044048"], "unii": ["XF417D3PSL", "R16CO5Y76E", "8MDF5V39QO"], "rxcui": ["1872085", "1872088"], "spl_set_id": ["49b73bd5-6465-05eb-e054-00144ff88e88"], "pharm_class_cs": ["Anti-Inflammatory Agents, Non-Steroidal [CS]"], "pharm_class_pe": ["Decreased Coagulation Factor Activity [PE]", "Decreased Prostaglandin Production [PE]", "Decreased Platelet Aggregation [PE]"], "pharm_class_epc": ["Calculi Dissolution Agent [EPC]", "Anti-coagulant [EPC]", "Nonsteroidal Anti-inflammatory Drug [EPC]", "Platelet Aggregation Inhibitor [EPC]"], "pharm_class_moa": ["Acidifying Activity [MoA]", "Calcium Chelating Activity [MoA]", "Cyclooxygenase Inhibitors [MoA]"], "manufacturer_name": ["Bayer HealthCare LLC."], "is_original_packager": [true]}, "finished": true, "packaging": [{"sample": false, "description": "12 PACKET in 1 CARTON (0280-0211-24)  / 2 GRANULE, EFFERVESCENT in 1 PACKET", "package_ndc": "0280-0211-24", "marketing_start_date": "20110418"}], "brand_name": "Alka-Seltzer Extra Strength", "product_id": "0280-0211_45266611-610c-a481-e063-6394a90a1bf0", "dosage_form": "GRANULE, EFFERVESCENT", "pharm_class": ["Acidifying Activity [MoA]", "Anti-Inflammatory Agents", "Non-Steroidal [CS]", "Anti-coagulant [EPC]", "Calcium Chelating Activity [MoA]", "Calculi Dissolution Agent [EPC]", "Cyclooxygenase Inhibitors [MoA]", "Decreased Coagulation Factor Activity [PE]", "Decreased Platelet Aggregation [PE]", "Decreased Prostaglandin Production [PE]", "Increased Large Intestinal Motility [PE]", "Inhibition Large Intestine Fluid/Electrolyte Absorption [PE]", "Nonsteroidal Anti-inflammatory Drug [EPC]", "Osmotic Activity [MoA]", "Osmotic Laxative [EPC]", "Platelet Aggregation Inhibitor [EPC]"], "product_ndc": "0280-0211", "generic_name": "Anhydrous Citric Acid, Sodium Bicarbonate, and Aspirin", "labeler_name": "Bayer HealthCare LLC.", "product_type": "HUMAN OTC DRUG", "brand_name_base": "Alka-Seltzer Extra Strength", "active_ingredients": [{"name": "ANHYDROUS CITRIC ACID", "strength": "1000 mg/1"}, {"name": "ASPIRIN", "strength": "500 mg/1"}, {"name": "SODIUM BICARBONATE", "strength": "1985 mg/1"}], "application_number": "M001", "marketing_category": "OTC MONOGRAPH DRUG", "marketing_start_date": "20110411", "listing_expiration_date": "20261231"}