alka-seltzer plus severe cold powerfast fizz orange zest

Generic: aspirin, chlorpheniramine maleate, phenylephrine bitartrate

Labeler: bayer healthcare llc.
NDC Directory HUMAN OTC DRUG OTC MONOGRAPH DRUG Inactive Finished

Drug Facts

Product Profile

Brand Name alka-seltzer plus severe cold powerfast fizz orange zest
Generic Name aspirin, chlorpheniramine maleate, phenylephrine bitartrate
Labeler bayer healthcare llc.
Dosage Form TABLET, EFFERVESCENT
Routes
ORAL
Active Ingredients

aspirin 325 mg/1, chlorpheniramine maleate 2 mg/1, phenylephrine bitartrate 7 mg/1

Manufacturer
Bayer HealthCare LLC.

Identifiers & Regulatory

Product NDC 0280-0020
Product ID 0280-0020_2be96d7c-dcfc-3eaf-e063-6394a90a5220
Product Type HUMAN OTC DRUG
Marketing Category OTC MONOGRAPH DRUG
Application Number M012
Listing Expiration 2026-12-31
Marketing Start 2020-07-01

Pharmacologic Class

Established (EPC)
nonsteroidal anti-inflammatory drug [epc] platelet aggregation inhibitor [epc]
Mechanism of Action
cyclooxygenase inhibitors [moa]
Chemical Structure
anti-inflammatory agents, non-steroidal [cs]
Physiologic Effect
decreased prostaglandin production [pe] decreased platelet aggregation [pe]

Normalized Code Variants

Searchable formats for this product NDC code

Digits Only 02800020
Hyphenated Format 0280-0020

Supplemental Identifiers

RxCUI
1536840
UPC
0016500598855
UNII
R16CO5Y76E V1Q0O9OJ9Z 27O3Q5ML57
NUI
N0000000160 N0000008836 M0001335 N0000175722 N0000175578 N0000008832

Packaging Origin

Original Packager
true

Resolved Product View

Precedence rule: structured NDC data is preferred, falling back to linked label metadata when unavailable. Source tags show the origin of each value.

Resolved Identity

Brand Name alka-seltzer plus severe cold powerfast fizz orange zest (source: ndc)
Generic Name aspirin, chlorpheniramine maleate, phenylephrine bitartrate (source: ndc)
Application Number M012 (source: ndc)
Routes
ORAL
source: ndc

Resolved Composition

Strengths
  • 325 mg/1
  • 2 mg/1
  • 7 mg/1
source: ndc
Packaging
  • 10 POUCH in 1 CARTON (0280-0020-01) / 2 TABLET, EFFERVESCENT in 1 POUCH
  • 12 POUCH in 1 CARTON (0280-0020-02) / 2 TABLET, EFFERVESCENT in 1 POUCH
source: ndc

Packages (2)

0280-0020-01 10 POUCH in 1 CARTON (0280-0020-01) / 2 TABLET, EFFERVESCENT in 1 POUCH 0280-0020-02 12 POUCH in 1 CARTON (0280-0020-02) / 2 TABLET, EFFERVESCENT in 1 POUCH

Ingredients (3)

aspirin (325 mg/1) chlorpheniramine maleate (2 mg/1) phenylephrine bitartrate (7 mg/1)

Linked Drug Pages (1)

Alka-Seltzer Plus Severe Cold PowerFast Fizz Orange Zest ndc-match (0.9)

Raw FDA Data

View complete raw FDA NDC JSON payload 
{"route": ["ORAL"], "spl_id": "2be96d7c-dcfc-3eaf-e063-6394a90a5220", "openfda": {"nui": ["N0000000160", "N0000008836", "M0001335", "N0000175722", "N0000175578", "N0000008832"], "upc": ["0016500598855"], "unii": ["R16CO5Y76E", "V1Q0O9OJ9Z", "27O3Q5ML57"], "rxcui": ["1536840"], "spl_set_id": ["a23a6db6-4585-2882-e053-2a95a90ab01a"], "pharm_class_cs": ["Anti-Inflammatory Agents, Non-Steroidal [CS]"], "pharm_class_pe": ["Decreased Prostaglandin Production [PE]", "Decreased Platelet Aggregation [PE]"], "pharm_class_epc": ["Nonsteroidal Anti-inflammatory Drug [EPC]", "Platelet Aggregation Inhibitor [EPC]"], "pharm_class_moa": ["Cyclooxygenase Inhibitors [MoA]"], "manufacturer_name": ["Bayer HealthCare LLC."], "is_original_packager": [true]}, "finished": true, "packaging": [{"sample": false, "description": "10 POUCH in 1 CARTON (0280-0020-01)  / 2 TABLET, EFFERVESCENT in 1 POUCH", "package_ndc": "0280-0020-01", "marketing_start_date": "20200701"}, {"sample": false, "description": "12 POUCH in 1 CARTON (0280-0020-02)  / 2 TABLET, EFFERVESCENT in 1 POUCH", "package_ndc": "0280-0020-02", "marketing_start_date": "20230330"}], "brand_name": "Alka-Seltzer Plus Severe Cold PowerFast Fizz Orange Zest", "product_id": "0280-0020_2be96d7c-dcfc-3eaf-e063-6394a90a5220", "dosage_form": "TABLET, EFFERVESCENT", "pharm_class": ["Adrenergic alpha1-Agonists [MoA]", "Anti-Inflammatory Agents", "Non-Steroidal [CS]", "Cyclooxygenase Inhibitors [MoA]", "Decreased Platelet Aggregation [PE]", "Decreased Prostaglandin Production [PE]", "Histamine H1 Receptor Antagonists [MoA]", "Histamine-1 Receptor Antagonist [EPC]", "Nonsteroidal Anti-inflammatory Drug [EPC]", "Platelet Aggregation Inhibitor [EPC]", "alpha-1 Adrenergic Agonist [EPC]"], "product_ndc": "0280-0020", "generic_name": "aspirin, chlorpheniramine maleate, phenylephrine bitartrate", "labeler_name": "Bayer HealthCare LLC.", "product_type": "HUMAN OTC DRUG", "brand_name_base": "Alka-Seltzer Plus Severe Cold PowerFast Fizz", "brand_name_suffix": "Orange Zest", "active_ingredients": [{"name": "ASPIRIN", "strength": "325 mg/1"}, {"name": "CHLORPHENIRAMINE MALEATE", "strength": "2 mg/1"}, {"name": "PHENYLEPHRINE BITARTRATE", "strength": "7 mg/1"}], "application_number": "M012", "marketing_category": "OTC MONOGRAPH DRUG", "marketing_start_date": "20200701", "listing_expiration_date": "20261231"}