waverley pharma inc - Medication Listings
Browse 2 medications manufactured by waverley pharma inc. Open a product record to review dosage forms, strengths, packaging, and related navigation.
Bortezomib for Injection, a proteasome inhibitor, contains bortezomib which is an antineoplastic agent. Bortezomib is a modified dipeptidyl boronic acid. The chemical name for bortezomib, the monomeric boronic acid, is [(1S)-3-methyl-1- [[(2R)- 3-phenyl- 2-(pyrazine-2-carbonylamino) propanoyl] amino] butyl] boronic acid. Bortezomib has the following chemical structure: The molecular weight is 384.24. The molecular formula is C 19 H 25 BN 4 O 4. The solubility of bortezomib, as the monomeric boronic acid, in water is 3.3 to 3.8 mg/mL in a pH range of 2 to 6.5. Bortezomib for Injection is available for intravenous injection or subcutaneous use. Each single-dose vial contains 3.5 mg of bortezomib as a sterile lyophilized powder. It also contains the inactive ingredient: 35 mg mannitol, USP. The product is provided as a mannitol boronic ester which, in reconstituted form, consists of the mannitol ester in equilibrium with its hydrolysis product, the monomeric boronic acid. The drug substance exists in its cyclic anhydride form as a trimeric boroxine. Chemical Structure
Pemetrexed for Injection USP is a folate analog metabolic inhibitor. The drug substance, pemetrexed disodium hemi-pentahydrate, has the chemical name L-glutamic acid, N -[4-[2-(2-amino-4,7-dihydro-4-oxo-1 H -pyrrolo[2,3- d ]pyrimidin-5-yl)ethyl]benzoyl]-, Disodium, hemi-pentahydrate with a molecular formula of C 20 H 19 N 5 Na 2 O 6 •2.5H 2 O and a molecular weight of 516.37. The structural formula is as follows: Pemetrexed for Injection USP is a sterile white-to-light yellow or green-yellow lyophilized powder in single-dose vials to be reconstituted for intravenous infusion. Each 100-mg vial of Pemetrexed for Injection USP contains 100 mg pemetrexed (equivalent to 110.3 mg pemetrexed disodium hemi-pentahydrate) and 106 mg mannitol. Each 500-mg vial of Pemetrexed for Injection USP contains 500 mg pemetrexed (equivalent to 551.4 mg pemetrexed disodium hemi-pentahydrate) and 500 mg mannitol. Hydrochloric acid and/or sodium hydroxide may have been added to adjust pH. Structural Formula
About waverley pharma inc
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